Human-relevant data for more predictive and ethical drug development

The Challenge & Our Solution

Central nervous system drug development remains highly inefficient, with over 94% of drug candidates failing clinical development. A major contributor is the limited human predictivity of existing preclinical models. Animal models often fail to reflect human biology, and many conventional in vitro systems are static, failing to reproduce physiological flow, tissue architecture, and the cellular microenvironment. This is particularly critical in blood–brain barrier research, where current models are either too simplistic or too complex to scale.

FLUIDIC Biosciences develops flexible and modular dynamic culture technologies combining human cells, biomimetic nanofibre scaffolds, and controlled flow conditions. This creates more physiologically relevant in vitro models. Our first major application is a 3D tubular blood–brain barrier model designed to reproduce key features of human blood-vessel architecture and its surrounding cellular microenvironment.

Our Core Advantages

The FLUIDIC Platform Attributes

Human-Relevant

Dynamic Culture

Biomimetic Design

Ethical & Clean

Using human cells to generate data with enhanced predictive power, ensuring greater translatability to clinical outcomes.

Recreating physiological flow conditions rather than relying exclusively on static culture, mimicking in vivo environments.

Utilising nanofibre technology to reproduce key structural features of the cellular microenvironment, for realistic models.

Xeno-free and PDMS-free systems support ethical research and reduce drug absorption risks associated with conventional microfluidics.

Our Offerings

Specialised Services & Models

BBB Permeability Screening

Advanced BBB Platform Packages

Pilot studies available to determine compound permeability across the blood-brain barrier with enhanced predictivity.

Comprehensive solutions for blood-brain barrier studies, leveraging our 3D tubular models for high-fidelity data.

Nanofibre Culture Inserts

Innovative biomimetic inserts for dynamic in vitro cell culture, available for pilot studies and custom applications.

Partner with FLUIDIC Biosciences for human-relevant data that accelerates drug discovery and development, reducing costs and ethical concerns.