Precision BBB Modeling

Dynamic Flow for Predictive BBB Models

Our 3D tubular blood-brain barrier models combine human cells, biomimetic nanofibre scaffolds, and controlled flow for unparalleled physiological relevance. Reduce preclinical failure rates with human-relevant data.

Our CNS functional screening services are designed to assess cellular health, morphology and functional responses in human-relevant central nervous system models.

CNS Functional Screening

Studies may include cell viability and cytotoxicity assessment, neurite morphology or outgrowth analysis and functional cellular readouts.

Services can be tailored according to the model, compound and objectives of each project.

Biomimetic Tubular Geometry

Reproducing Physiological Microenvironments

Our 3D tubular architecture meticulously mimics human microvascular geometry, fostering natural lumen fluid dynamics. This design facilitates precise astrocytic interaction, crucial for accurate in vitro BBB modeling and enhanced translatability.

Unlike static systems, our dynamic models ensure continuous shear stress, maintaining functional tight junctions and accurate trans-endothelial resistance. This translates to more reliable data for CNS drug development.

Empirical Advantages

Quantifiable Performance Metrics

0%

PDMS Absorption

Human-Relevant

Physiological Shear Stress

Automated

TEER Tracking

Advance Your CNS Drug Discovery

Partner with FLUIDIC Biosciences to leverage our advanced 3D BBB models. Discuss your specific project requirements and initiate a pilot permeability study for more predictive outcomes.